Research digital skills training 2021
Calcium signalling in salivary gland acinar cells
Dr. John Rugis1, Professor James Sneyd1 Department of Mathematics, University of Auckland; David Yule2, Medical Center, University of Rochester.
Figure 1 – Graphical representation of the calcium signalling and fluid flow model.
Figure 2 – Seven cell structural mesh, used for numerical modelling.
Figure 3 – Calcium signalling and fluid flow simulation results displayed in interactive 3D.
- Pages, N., Vera-Sigüenza E, Rugis, J., Kirk, V., Yule, D. I., & Sneyd, J. (2019). A Model of Ca2+ Dynamics in an Accurate Reconstruction of Parotid Acinar Cells. Bulletin of mathematical biology, 81 (5), 1394-1426
- Vera-Sigüenza E, Pages, N., Rugis, J., Yule, D. I., & Sneyd, J. (2019). A Mathematical Model of Fluid Transport in an Accurate Reconstruction of Parotid Acinar Cells. Bulletin of mathematical biology, 81 (3), 699-721
- Vera-Sigüenza E, Pages, N., Rugis, J., Yule, D. I., & Sneyd, J. (2020). A Multicellular Model of Primary Saliva Secretion in the Parotid Gland. Bulletin of mathematical biology, 82 (3)
Our work is heavily reliant on the computer resources and consultation services provided by both the Centre for eResearch and NeSI (New Zealand eScience Infrastructure). Quite simply put, we could not have extended our project to its current scope and depth without these resources. Special thanks to Nick Young of the Centre for eResearch for helping us create a Hololens visualisation movie showing our simulation results.